Research & Evidence

Clinical Evidence

Peer-reviewed research supports the advanced elastography systems we supply, with published data on accuracy and reliability in liver fibrosis assessment.

0.95
AUROC Score
Advanced fibrosis/cirrhosis (≥F3–F4), published cohorts
96.5%
Success Rate
Valid measurements (large NAFLD FibroTouch study)
~0.71–0.89
AUROC (≥F2)
Typical range across published studies (varies by cohort)
15+
Publications
Peer-reviewed studies

Peer-Reviewed Research

Key Studies

FibroTouch / iLivTouch in NAFLD and Comparative TE Literature

Multiple peer-reviewed sources (Various) • See primary publications and reviews

Published work reports FibroTouch NAFLD cohort measurement success around 96.5% in a large study. AUROC for ≥F2 fibrosis varies by study (commonly roughly 0.71–0.89); higher AUROC values (including ~0.94–0.96) align with advanced fibrosis/cirrhosis thresholds (≥F3–F4) in several cohorts. Obesity, narrow intercostal space, and ascites can limit reliability for any elastography modality.

Key Findings

  • ~96.5% measurement success in large published NAFLD FibroTouch cohort
  • AUROC for ≥F2 depends on population; ~0.95 values align with ≥F3–F4 in published data
  • Compare FibroScan M vs XL probes when interpreting high-BMI performance

Comparative Failure Rates: VCTE vs 2D Shear Wave Elastography in Chronic Liver Disease

Hepatology and Radiology journals (2022–2024) • Sjöman et al. and related cohort studies

Comparative studies in chronic liver disease populations report VCTE (FibroScan) failure rates of approximately 11.6% vs 5.16% for guided elastography. In cases where VCTE returned no valid result, guided elastography provided a valid measurement in approximately 61% of those patients. Failure rates are substantially higher in patients with BMI >30 using the standard M probe.

Key Findings

  • VCTE failure rate ~11.6% vs guided TE ~5.16% in CLD populations
  • Guided TE rescues ~61% of cases VCTE could not complete
  • Guided acquisition addresses the root cause of failure: inability to visualise probe placement

Clinical Guidelines

Supported by Leading Bodies

EASL

EASL

European Association for the Study of the Liver

Liver elastography is recommended as a first-line assessment for liver fibrosis in patients with chronic liver disease.

AASLD

AASLD

American Association for the Study of Liver Diseases

Non-invasive tests including elastography should be used for initial fibrosis assessment, reserving biopsy for indeterminate cases.

GESA

GESA

Gastroenterological Society of Australia

Elastography-based assessment is recommended for MAFLD staging and monitoring in the Australian clinical context.

See the evidence firsthand

Schedule a demonstration to see supplied guided elastography accuracy and reliability in action.